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Response caching allows you to cache model responses, which can significantly improve response times and reduce API costs during development and testing.
For a detailed overview of response caching, see Response Caching.
This is different from Anthropic’s prompt caching feature. Response caching caches the entire model response, while prompt caching caches the system prompt to reduce processing time.

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Basic Usage

Enable caching by setting cache_response=True when initializing the model. The first call will hit the API and cache the response, while subsequent identical calls will return the cached result.
cache_model_response.py
import time

from agno.agent import Agent
from agno.models.anthropic import Claude

agent = Agent(model=Claude(id="claude-sonnet-4-5", cache_response=True))

# Run the same query twice to demonstrate caching
for i in range(1, 3):
    print(f"\n{'=' * 60}")
    print(
        f"Run {i}: {'Cache Miss (First Request)' if i == 1 else 'Cache Hit (Cached Response)'}"
    )
    print(f"{'=' * 60}\n")

    response = agent.run(
        "Write me a short story about a cat that can talk and solve problems."
    )
    print(response.content)
    print(f"\n Elapsed time: {response.metrics.duration:.3f}s")

    # Small delay between iterations for clarity
    if i == 1:
        time.sleep(0.5)

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Usage

1

Set up your virtual environment

uv venv --python 3.12
source .venv/bin/activate
2

Set your API key

export ANTHROPIC_API_KEY=xxx
3

Install dependencies

uv pip install -U anthropic agno
4

Run Agent

python cache_model_response.py